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Biography |
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Mona K. Marei BDS, MSCD, PhD. Professor of prosthodontics, Head of Tissue Engineering Laboratories, Faculty of Dentistry, Alexandria University, Egypt. Prof. Marei is the Founder of Tissue Engineering Science and Technology in Egypt. She is a board member of higher council of industrial technology-Ministry of scientific research / Academy of Scientific Research and Technology, Egypt 2009-present time. She is also a board member in the national council – governmental presidential office in Egypt for genetic engineering/education-science and technology 2006-present time. Prof. Marei is an International African Advisor board member in African Renaissance Institute of Science and Technology 2005-present time. She is also a board executive member in the African Material Research Society. She is an International research advisory board member/Lehigh International Materials Institute for new functionality in glass USA 2008-present time .Prof. Marei is an executive editorial board member in Tissue Engineering –journal part A,B and C. She is also an Associate editors in the Annals of Biomedical Engineering 2010. Editorials board member in the international journal of Artificial Organs 2010. She is a peer reviewer in Eastern Mediterranean Health journal. Prof. Marei is the principal investigator of number of national and international research projects in the field of tissue engineering. She supervised many master/doctoral degree in the related disciplines of regenerative medicine. Prof. Marei organized several workshops, and public activities related to the field. She has several publications and patent and reviews numerous articles, academic and educational programs pertained to the field of tissue engineering and regenerative medicine, biotechnology education and advanced material technology. Prof. Marei received many awards, medals and certificates.
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Abstract |
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For more than 50 years, Tissue/organs transplants and bionic implants have been used successfully to replace human parts damaged by injuries or diseases. However both of these methods have significant drawbacks. A new approach to tissue restoration is regenerative therapy, which promised to be one of the biomedical revolution of the 21th century, that can address the current unmet clinical needs. It drives its power from the application of the principles and methods of engineering and life sciences toward understanding the structure/functional relationships in normal and pathological status. Despite significant advances in the field, which have resulted in successful engineering of living skin, cartilage, bone... etc., the tissue function depends on cells (~10µm) to functional subunit (100µm-1mm) that coordinate organ function. With this complexity of native tissues, the engineering of living tissue is understanding a major conceptual and methodological transformation in an effort to implant in-vitro processes that mimic in-vivo tissue development. Indeed, recent work has indicated that interaction of the concepts of developmental biology, engineering and manufacture using could modify methods used currently to recapitulate phenomena as in-vivo tissue development. The incorporation of improved fabrication strategy have led to dramatic enhancement in the complexity and biomimercy of today's engineering living tissues and organs. A new era is a head of us in which therapeutic and pharmaceutical application of tissue engineering will take centre stage and replace convectional medicine and drug therapy.
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