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Biography |
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Rafael RANGEL-ALDAO received his M.D. from University Central of Venezuela, and Ph.D. at the Department of Molecular Biology, Albert Einstein College of Medicine, New York. He is an Invited Professor of Digital Molecular Medicine at Simon Bolivar University, and CEO of Summum Net, a biotechnology company of preventative health and wellness. For a thirty year span, Dr. Rangel-Aldao has served both in the academic sector as professor of biotechnology at several major institutions of Venezuela (1979-2009), and Director of Research and Innovation at Empresas Polar (1987-2005), the largest food conglomerate of Venezuela and the third of Latin America. Prof. Rangel-Aldao has also published extensively in a wide range of fields from biochemistry, molecular biology, chemistry, plant physiology, and biomedical research, to food product development, and agricultural research and plant breeding. Rangel-Aldao is author of several triadic patents in biotechnology applied to both the food and biomedical industries.
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Abstract |
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A Systems Biology Approach to Translational Medicine and Wellness in Venezuela
Systems biology is on the verge of producing radical changes in clinical medicine by facilitating the prediction and prevention of major causes of morbidity world-wide, in particular those that are the most common and costly chronic ailments such as cardiovascular disease, cancer, obesity and type-2 diabetes. These diseases seem to be inter-related by networks of biological information that are regulated by common hubs made of genes and/or regulatory proteins, especially those pertaining to both the stress and the chronic inflammation response. Diseases are then no longer considered as separate nosologic entities, but the consequence of disequilibrium of such complex networks spanning the individual´s physiology and the nature and impact of its environment. The emphasis is now on how to collect, from normal subjects, enough network information of predictive value to preserve a person´s wellness as well as to avoid or retard the advent of disease.
The author will present an experimental attempt along these lines of reasoning, with a multidisciplinary approach organized in the form of stacked networks of collaboration between scientists, health care professionals, volunteers and their employers participating in such a program. |
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