Neuropathology

Methylmercury poisoning exhibits a variety of neuropathological features from severe changes at the early stage to mild changes. In the adult and infant type, predilection sites of the changes are clear; calcarine, post-central, pre-central, and superior temporal cortices are most vulnerable, whereas the changes in the brains of fetal type are less-localized, and show hypoplasia or developmental arrest, rather than neuronal destruction.