![](img006.GIF) |
Earlier
in 1898, Behring and Wernicke had found that immunity to diphtheria could be produced by
the injection into animals of diphtheria toxin neutralized by diphtheria antitoxin, as
Smith in 1907-09 had suggested that such toxin-antitoxin mixtures might be used to
immunize man against this disease. It was Behring, however, who announced, in 1913, his
production of a mixture of this kind, and subsequent work which modified and refined the
mixture originally produced by Behring resulted in the modern methods of immunization
which have largely banished diphtheria. |