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damokidebuleba gid-is garTulebebsa da sisxlSi dxw qolesterinis dones Soris bolo drois dakvirvebebis mixedviT, romelTa drosac gamoiyeneboda statinebi. bolo drois dakvirvebebma, romlebSic gaerTianebuli iyo 30 817 avadmyofi, aCvena TiTqmis pirdapirproporciuli damokidebuleba dxw qolesterinsa da gid-is garTulebebs Soris. pirveladi (WOSCOPS) da meoreuli (CARE, 4S) profilaqtikisadmi miZRvnili kvlevebidan gamomdinare dxw qolesterinis donis Semcirebas sisxlSi mosdevs gid-is garTulebebis Semcirebac.sahaero Zalebis/teqsasis koronaruli aTerosklerozis pirveladi profilaqtikisa (AFCAPS/TexCAPS) da pravastatiniT iSemiuri daavadebis xangrZlivi meoreuli profilaqtikis (LIPID) dakvirvebebma aCvena, rom msgavsi Sedegebia lipidebis Sualeduri maCveneblebis mqone adamianebSic.am dakvirvebebze dayrdnobiT SeiZleba gavakeToT ori mTavari daskvna: dxw qolesterinis Semcireba iwvevs gid-is garTulebebis Semcirebas arakardiuli mizezebiT gamowveuli sikvdilianobis mniSvnelovani zrdis gareSe. dxw qolesterinis Semcirebis sikeTe vlindeba mosaxleobis im fenaSic, romelsac aReniSneba qolesterinis Sualeduri maCveneblebi. wasakiTxi literatura: Shepherd J et al. N Engl J Med. 1995;333:1301-1307. 4S Study Group. Lancet. 1995;345:1274-1275. Sacks FM et al. N Engl J Med. 1996;335:1001-1009. Downs JR et al. JAMA. 1998;279:1615-1622. |