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Liver Function
Tests (LFTs): LFTs include a number of markers that help determine liver
status. These include ALT (SGPT), AST (SGOT), LDH, alkaline phosphatase and
total bilirubin. Elevated liver enzymes are commonly caused by certain
medications. Elevated enzyme levels can also be caused by liver disease such
as hepatitis B or C, injuries, and tumors. Abnormal liver function test
levels are common in 60-70% of people with HIV, but liver failure is
unusual. High alkaline phosphatase levels along with normal bilirubin levels
can show serious disease and are often seen in people with Mycobacterium
avium Complex (MAC), cytomegalovirus (CMV), histoplasmosis, drug side
effects or Kaposi's Sarcoma. Bilirubin, a product of dead red blood cells,
is eliminated through the liver. High bilirubin levels in the blood can
indicate hepatitis (associated with a yellow skin color), bile duct
obstruction and other liver problems. |