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HERS考察了给予冠心病女性受试者固定剂量的雌激素和MPA的随机化远景实验中雌激素替换与CHD危险下降之间可观测的联系。
参考文献：
Hulley S, Grady D, Bush T,
Furberg C, Herrington D, Riggs B, Vittinghoff E, for the Heart and
Estrogen/progestin Replacement Study
(HERS) Research Group. Randomized trial of estrogen plus progestin
for secondary prevention of coronary heart disease in postmenopausal
women. JAMA 1998;280:605-613
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