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Incubation
period usually 2-4 days. Upper respiratory disease, acute or subacute,
subclinical/mild/severe. Usually lethargy, anorexia, pyrexia, respiratory tract signs,
vesicles & ulcers of the oral epithelium (2-5 mm). Also, dyspnoea, ocular & nasal
discharges, conjunctivitis, rhinitis, tracheitis, pneumonia, stiff gait. Strains differ
in tropism & virulence; some cause upper & lower respiratory disease, others only
upper respiratory disease, some associated with subclinical infections. Morbidity high,
mortality low; often seen in kittens within 24-48 hours of infection. Mortality increased
by concurrent viral or bacterial infections. Recovery followed by prolonged carrier state.
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