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Influenza virus was first isolated from pigs in 1931 by Shope. This swine virus is antigenically related to the influenza virus isolated by Smith, Andrewes and Laidlaw in 1933. It is of historical note that the virus was isolated from a specimen obtained from C. H. Andrewes himself. Both these viruses are antigenically similar (same serotype) and are serologically related to the influenza virus that caused the 1918 pandemic.