The general principles seen with antimicrobial agents and bacteria are also observed with eukaryotic cells. The slide shows a mutant selection curve with the yeast Candida glabrata applied to miconazole-containing agar plates. In this experiment colonies were recovered from drug-containing agar, restreaked on drug-free agar, and then retested on drug-containing agar to establish that the mutants were stable. Notice that the mutant recovery frequency (plateau) is very high and that the selection window is very wide. These features are expected to cause resistant mutants to be readily enriched by miconazole treatment. As expected, the selection curve was shifted by the presence of resistance mutations, which in this case are undefined. Similar results were obtained with Candida albicans. The slide shows unpublished work by Wang et al., Public Health Research Institute.