The human population explosion and overuse of the land are changing the ecology to a drier one associated with the global warming trend. Game animals as reservoirs for parasites are being reduced. Cattle expand at the expense of forest. The distribution of trypanosomiasis in domestic and wild animals is little known. Human targets as rural versus civic populations are distinct. Further, the sylvatic versus urban cycle of given diseases is changing, because some vectors have adapted more and more to urbanization. More, the changes in the rural-urban interface are little known. The ecology is becoming drier as forests are logged off in all parts of the world as overpopulation supports povery. Which triatomids fit into this drier cleared epidemiology? In the Brazilian Amazon, forest fires in the name of landclearing for the beef industry are notorious, but also wellrecognized throughout the planet earth.