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Fortunately, medical informatics is beginning to mature. The central technologies will be data acquisition, decision support, information distribution/storage, access and distant education. Once biosignals or images are measured, the information systems will need to acquire this information. This can be in a home personal computer, local home server, or commercial secure website. This will be a personal data site, with all the appropriate security and privacy integrated. Powerful decision support systems will analyze the massive amounts of data, comparing it to the individual’s legacy information to determine any significant changes. Only those changes considered substantially outside of norms for that individual will be used in an alert, first to the individual, and then to a healthcare provider. The systems that analyze the information will likely be distributed throughout the net, since it is unlikely all the decision support systems could or would be contained on a single website. Secure distribution and storage of the medical data will be an ongoing challenge, as will be determining access to the information. Not only will the person or healthcare provider want access to individual information, but even more important will be access to the appropriate medical educational and reference material. Intelligent agents will be needed to sift through the petabytes of information to bring only that information relative to the person’s query. It will be essential to provide trusted preventive medicine information through the Internet in a manner that is usable by the individual patients, with a human user interface that stimulates and encourage healthful behavior rather than confuses or frustrates those seeking advice. When necessary, the Internet will be made available for tele-consultation, using systems that are reminiscent of today’s primitive devices but which will greatly facilitate the exchange of medical information and enhance the doctor-patient relationship. Current advances using Internet 2 applications suggest that such relationships will be fully interactive, 3-D immersive experiences which give the participants the sense of the other’s presence – virtual reality over the Internet is referred to as tele-immersion.