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Cocaine and Neurotransmission
Drugs of abuse are able to interfere with this normal communication
process in the brain.
Cocaine, for example, blocks the removal of dopamine from the
synapse by binding to the dopamine transporters.
As shown in this slide, this results in a buildup of dopamine
in the synapse. In turn, this
causes a continuous stimulation of receiving neurons, probably
responsible for the euphoria reported by cocaine abusers.
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