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This is illustrated here in a figure taken from
a recent paper by Elsbeth Walker. A heterozygote between the paramutable R-r allele and the paramutagenic R-mb allele gives rise to a strongly pigmented F1 heterozygote. When the heterozygote is used as the male parent in a backcross to a colorless allele, the resulting heterozygote is very much more weakly pigmented than its parent. You will also note that the effect appears to be more pronounced when the paramutable R-r allele is transmitted through the male than through the female. Now let’s look at what’s known about the molecular basis paramutagenicity and paramutability. |