Cats, perphaps the original host. Contact infection through abraded skin. A variety of lesions from 'shallow, crater-like ulcers filled with white pus' to 'flat red, glistening areas'. They are usually on paws, head or lips and may generalise or cause pruritis. The respiratory form is rare but fatal.

Man Cats or cows can infect man to produce pocks on the forearm or face. These can generalize if the person is immunosuppressed, so take care.