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The method of triads is a technique for
estimating the correlation between an observed measure of exposure and the true, but
unknown, exposure value. The correlation in this case is referred to as the validity
coefficient (VC). This technique was first applied by Dr. Rudolph Kaaks for use in
validation studies in nutritional epidemiology. Application of the method of triads
requires at least 3 measurements of the same exposure and assumes that all the 3
measurements are linearly related to the true exposure (T). First, we
will briefly refer to continuous exposures and the associated measurement error. |