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The hs-CRP
phenomenon appears to predict systemic vascular events as well as MI or stroke. These
prospective data, again deriving from middle-aged men, indicate that CRP levels are higher
at baseline among those apparently healthy individuals who subsequently develop either
intermittent claudication or a need for peripheral arterial surgery over the next 6 to 8
years of their lives. Reference:
Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Plasma concentration of
C-reactive protein and risk of developing peripheral vascular disease. Circulation
1998;97:425-428.
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