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- An
overestimate of true folate intake among Mexican American women would have made effects
appear weaker than they were - The FFQ doesn’t distinguish postconception time from preconception time - Many women adhere to a healthier diet during pregnancy - These women may have selectively recalled healthy (folate-rich) foods consumed after the neural tube closed (~1 month postconception) rather than their more relevant preconception intake - If case and control women misclassified their exposures to the same extent, estimated odds ratios would have been biased towards the null |