Moreover, there may be instances where preventive interventions are not advised. This slide portrays several criteria that should be considered when contemplating an intervention. These include the severity of the disease (or importance of the problem), how frequent it occurs, the type of screening or intervention contemplated, whether or not the intervention has been shown to work, it’s cost and it’s safety. Ideally, you want to pursue an intervention that addresses a serious condition which occurs frequently in the population. An effective treatment for the condition should exist and an acceptable intervention should be available. The intervention should have data to show that it works, is safe and has a relatively reasonable cost.