Topical nitroglycerin cream may provide temporary, safe and effective relief from pain (14).

Topical lidocaine has shown promising results in some women, as it helps to break the nociceptor input to the CNS (15).

Capsaicin cream, an immune response modifier imiquimod, is being tried, but efficacy data do not exist (16).

(14) Walsh KE,Berman JR, Berman LA,Vierregger K.Safety and efficacy of topical nitroglycerine for treatment of vulvar pain in women with vulvodynia:a pilot study.J Gend Specif Med 2002;5:21-27

(15) New concepts in vulvodynia,Edwards,Libby MD,Am J Obstet Gynecol,Volume 189(3)Supplement,September 2003,ppS24-S30