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We have much evidence now that
there is development of atherosclerosis beginning in infancy. From the Bogalusa Heart
Study, we have overwhelming proof that fatty streaks form in infancy, followed by fibrous
plaques, and eventually full blown atherosclerosis. The rates at which this occurs depend
on risk factors such as obesity, physical inactivity, hypertension, diabetes,
hypercholesterolemia, smoking and of course family history, racial group and socioeconomic
factors. Berenson et al. N Engl J Med 1998; 338:1650-56. |