•Hg, As and Se concentrations in channel catfish fillet were not significantly different in the Pittsburgh Pool as originally hypothesized. Channel catfish caught in highly legacy contaminated areas of the Monongahela River did not differ in flesh concentrations of Hg, As or Se from fish caught in the same pool but in the Allegheny River portion of the pool.

􀀹The Pittsburgh Pool may be considered a locked water system due to the lock and dam system on all area rivers.

􀀹Pollution discharged into the Pittsburgh Pool from industrialized sources and sewer overflows may be evenly distributed through the water body.

􀀹Fish caught at each location within the Pittsburgh Pool may range throughout the pool.Volz et al.,2007; APHA Conference: http://www.pitt.edu/~cdv5/