Acaricides to help control the vector. They reduce tic-bite pyaemia as well as louping ill.

Initially formalinised sheep spleen or brain from infected animals was used. This protected sheep but was also a means of transmitting scrapie.

Sheep kidney tissue culture virus inactivated with methanol is now commonly used as an annual vaccine in late pregnancy to provide maternal immunity. Lambs are not inoculated until >4 months old.

Vaccinate personnel at risk.

Reservoir hosts make control difficult.