1. Smith WL, Langen BR. Why there are two cyclooxygenase isoenzymes. J Clin Invest 2001;107: 1491-95.

2. Wallace JL. Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal anti-inflammatory drugs (NSAIDs). Am J Med 1999;107(6A):11-16.

3. Simon LS. Are the biologic and clinical erfects of the COX-2-specific inhibitors an advance compared with the effects of traditional NSAIDs? Curr Opin Rheumatol 2000;12:163-70.

4. Wallace, J.L. Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal antiinflammatory drugs (NSAIDs). Am. J. Med., 107 11S-16S, 1999.

5. McCormack K. Novel aspects of pain management, Opioids and beyond. J. Sawynok, A. Cowan (eds.). New York: John Wiley & Sons Inc. 1997.