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–Margaret
Dayhoff
–Atlas
of Protein Sequences
–Phylogenies,
evolution, amino acid substitution matrices (PAM) and discovering active
sites in enzymes
–PIR
SF Evolutionary
Family ,
iProClass
Functional site analysis and ontologies ,
iProLink
to literature
–Amos
Bairoch
–Manual
curation and annotation
–Highly
cross-referenced
•TREMBL
–Translation
of mRNAs (RefSeq), UniGene, open reading frames (ORFs) and predicted
genes from genomes
–Automatic
annotations
–Interpro
linked to domain and motif databases (CATH , PANTHER ,
PRINTs, PROSITE, pFAM, PIRSF, PRODOM, SCOP, SMART, SUPERFAMILY)
–Intron-exon
structure and links to ORFs, coding regions
–Protein
and nrPRO database SwissProt, PIR and translated genes/genomes
–Linked
to coding regions and intron/exon structure
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