Epidemiology and Demography Office--Jack Guralnik, M.D., Ph.D. 
The Epidemiology and Demography Office plans and conducts studies on: 
- Chronic diseases and on functional status and disability in the older population.
- The epidemiologic distribution and determinants of specific diseases such as coronary heart disease.
- The consequences of disease, especially the effects of chronic disease on functional limitations and the ability to remain independent in the community.
- The roles of behavioral, psychosocial, and demographic risk factors in the development of disease and disability.

Neuroepidemiology of Aging Office -- Lenore Launer, Ph.D.
The Neuroepidemiology Office was established in 1999. First year efforts have focused on formulating in-depth studies of selected mechanisms hypothesized to play a role in neurodegeneration; developing the research proposal on brain function in a study of genetic susceptibility and gene-environment interaction in health conditions common in old age; and developing analyses and initiating new projects using existing data and biologic specimens. Different markers of neurodegeneration are being studied to better understand the consistency and impact of various risk factors on brain disease.