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The host: B and T
cells All blood cells originate in the bone marrow though T lymphocytes mature in the thymus gland. T-cells are marked with specific histocapatability molecules in their surface membrane (called clusters of differentiation, or CD) that identify their immune function. All T-cells are marked with CD3, while those marked with CD4 are considered helper-inducer cells, and those marked with CD8 are cytotoxic T-lymphocytes (CTL or killer T-cells) or suppressor cells. NK stands for natural killer cell. CD4+ cells are infected with HIV when HIV binds both to the CD4 molecule and a molecule called fusin. Of course, CD8 cells also get infected with HIV.
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