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Each kilogram of adipose tissue contains about 7000 calories and a very strict
diet cutting back by 500 kcal a day, will lead to weight loss of around 0.5 kg
per week and loss of 7 kg in around 3 months.
Many individuals with refractory obesity may have limited success with different strategies. As new pharmacological agents (for people with BMI >27 kg/m2 with other health risks or problems, e.g., diabetes, or >30 kg/m2 without other health risks or problems) become available, they may prove to be effective. Studies on the long-term efficacy and safety of these methods are, however, needed. |