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Low high-density
lipoprotein cholesterol (HDL-C) levels (< 40 mg/dL) are associated with an increased
risk of coronary heart disease (CHD) even if the total cholesterol (Total-C) level is <
200 mg/dL. This slide shows the CHD incidence over 14 years among Framingham Study
subjects who were aged 48–83 years at baseline.1 Among those with HDL-C
levels < 40 mg/dL and Total-C < 200 mg/dL, 11.24% experienced a CHD event. This
incidence was virtually the same as that (11.91%) for subjects with HDL-C levels between
40–49 mg/dL and Total-C ? 260 mg/dL. References
1. Castelli WP, Garrison RJ, Wilson PW, et al. Incidence of coronary heart disease and
lipoprotein cholesterol levels: the Framingham Study. JAMA. 1986;256:2835–2838. |
