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Antiretroviral therapy not only reduces the risk of
MTCT, but also reduces the risk of sexual transmission because it decreases viral load,
reduces incidence of tuberculosis by strengthening the immune system, and promotes HIV
testing by giving hope that something can be done if HIV is diagnosed. More persons with
HIV may be diagnosed at earlier stages of infection and receive not only effective
treatment for themselves but also counseling about prevention of transmission to others.
The use of antiretroviral drugs, however, is complicated by the need for strict adherence
to avoid development of resistance, the complexity of current regimens, high cost, and the
possibility of side effects and toxicity from these agents. These side effects may
potentially be worsened in individuals with underlying malnutrition and anemia. |