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Based on the cut off points used by Cook applying a multiple test approach, as shown in the table, we can identify. Iron sufficient status: where biochemical tests present normal values. Iron depleted non-anemic: when iron stores (Serum Ferritin) are depleted but hemoglobin values are not affected. Iron deficient erithropoyesis: where a higher depletion is observed with erithropoyesis affected , but still normal hemoglobin values. Iron deficiency anemia: stage that represents the end point of a continuum iron depletion where hemoglobin has been affected. As it was mentioned, the final confirmation of these stages requires an examination of the response to iron supplementation.