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Kappa = (Po
- Pe)/(1
- Pe)
Where:
Po = A + D
Pe
= [(A+B)*(A+C) + (C+D)*(B+D)]/N2
Po = Proportion of
subjects observed to be
concordant*
Pe = Proportion of
subjects expected to be
concordant*,
based on chance alone
N
=Total number of subjects
*Where
both sources of data agree that subject either has presence or
absence of disease
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