Life
Cycle. Eggs are laid in the pulmonary arteries and
are trapped in capillaries where they hatch. The larvas emerge into alveoli
and move up the trachea to the pharynx where they are swallowed and passed
in the feces. Larvas enter snails or slugs and undergo 2 molts. Dogs become
infected by ingesting infected snails, slugs or their hosts. The 3rd stage
larvas migrate from the intestine into lymph nodes and to the pulmonary
arteries. The prepatent period is 7 weeks and adults may live in the host
for over 2 years..Clinical Features.
Obstruction of pulmonary arteries by adult worms and obstruction of
arterioles and capillaries by larvas lead to perivascular fibrosis and
endocarditis of the tricuspid valve. Sequels can be congestive cardiac
failure and cardiac insufficiency. Signs may include anorexia, coughing and
dyspnea.
Diagnosis. Demonstration of
larvas in feces and saliva.
Treatment and Control.
Levamisole, fenbendazole and mebendazole have been effective. Many other
deparasitizing drugs against nematodes work well.