It is evidently true with regard to patients with the maniacal depressive psychosis in a maniacal state, to chronic patients leading an autistic life or to patients with alcoholism and addictions. The quality of life subjective indices of such patients provide admittedly distorted outcomes due to the presence in the patients of pronounced psychological protection, such as a reactive formation, devaluation or negation. Such patients manifest a discrepancy between self-esteem in the process of filling out questionnaires and other emotion objective indicators. A mental patient in a mixed state can assess his/her well-being as the best he/she has ever had in his/her life and, a few hours later, commit an unexpected suicide (“If you manage in the morning to perceive the correct way of living, you may die by the evening” – Confucius). The correct interpretation of quality of life subjective indices by such patients can be achieved only when using additional correction sub-scales.