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front |1 |2 |3 |4 |5 |6 |7 |8 |9 |10 |11 |12 |13 |14 |15 |16 |17 |18 |19 |20 |21 |22 |23 |review |
The gap
between disease pathology and the identification and roles of causative
genes is a major problem of the genomic revolution. Another difficulty is
the selection of target genes with the best changes of making the long
journey from the bench to the clinic. Antisense oligonucleotides (oligos)
for gene functionalization (determining gene function) is of course vital to
gene therapty. |