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Lets talk about predictors of atherotrombotic risk in people
with diabetes and glucose intolerance. The excess risk of cardiovascular disease in
diabetic subjects is shared by those with impaired glucose tolerance and impaired fasting
glucose (in less degree). What these conditions have in common is a syndrome of resistance
to insulin action. Insulin sensitivity is universally present in patients with type 2
Diabetes and those with glucose intolerance. But even in people with normal glucose
tolerance there is a wide range of sensitivity to the action of insulin with many insulin
resistance subjects maintaining normal glucose tolerance. |