Advantages of varenicline include the following:
Varenicline is an oral formulation (twice-a-day dosing) that is easy to use.
Varenicline offers a new mechanism of action for persons who previously failed using other medications.
Early industry-sponsored trials suggest this agent is superior to bupropion SR.

Disadvantages of varenicline include the following:
The drug may induce nausea in up to one third of patients.

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