Distinction between “typical” and “atypical” groups is not clearly defined, but rests on:

Incidence of extrapyramidal side-effects (less in “atypical” group)

Efficacy in treatment – resistant group of patients

Efficacy against negative symptoms

Phenothiazines: Chlorpromazine, Triflupromazine, Thioridazine,Trifluoperazine and others.

Butyrophenones: Haloperidol, Trifluperidol, Droperidol, Penfluridol.

Thioxanthenes: Chlorpothixene, Thiothixene, Flupenthixol.

Others: Pimozide, Molindone, Loxapine, Reserpine.