|
|
|
front |1 |2 |3 |4 |5 |6 |7 |8 |9 |10 |11 |12 |13 |14 |15 |16 |17 |18 |19 |20 |21 |22 |review |
 |
2. Autonomic Nervous System
Neuroleptics have varying degrees of
α-adrenergic
blocking activity clorpromazine=triflupromazine>thioridazine>
fluphenazine>haloperidol>trifluoperazine>clozapine
>pimozide, i.e. more potent compounds have lower propensity.)
anticholinergic property of
neurolrptics is weak and may
be graded as thiridazine>chlorpromazine>triflupromazine>trifluoperazine =haloperidol
The phenothiazines have weak H1-
antihistamibic and anti-5-HT action as well.
|