Title:
Improving HIV Antiretroviral Therapy Adherence in Nigeria: implications for client and public health
Authors:
Shobowale, Oladipupo Oluwaseun
Publisher:
KIT - Royal Tropical Institute
Year:
2015
PAGE:
viii, 79
Language:
En
Subject:
Governance & HIV and AIDS
Keywords:
Adherence, adherence factors, antiretroviral therapy, adherence intervention strategies, people living with HIV, Nigeria
Abstract:
Background: Antiretroviral therapy (ART) adherence remains crucial to achieving therapeutic success in the management of HIV infection. Objective: To explore the patterns of ART adherence, assess the factors influencing ART adherence and identify effective interventions geared towards improving ART adherence among adult people living with HIV (PLHIV) in Nigeria. Methods: An explorative descriptive literature review was done to identify relevant information according to the study objectives. An ART adherence framework was adapted from Wekesa and Sabate to analyse the factors influencing adherence. Findings: A wide variation of ART adherence rates (14.9% to >95%) was observed in the studies conducted in Nigeria. Evident factors influencing ART adherence identified were forgetfulness, financial problems, stigma and discrimination, social support, availability of ART drugs, complexity of drug regimen, drug side effects and aspects of access to ART such as cost and distance. Relevant adherence intervention strategies were identified and included: enhanced counselling, peer support, communication technology (SMS), fixed dose combination and home-based care. Conclusions: Multiple interacting factors affect ART adherence among PLHIV. Furthermore, from study findings, major research gaps were identified such as lack of studies in PLHIV sub-populations (e.g. men who have sex with men and elderly PLHIV), cost analysis studies on adherence interventions and studies assessing long-term adherence. Recommendations: Need for further research in highlighted areas, adoption of outlined interventions, and expanded funding for constant supply of ART drugs and subsidization of ART-related services.
Organization:
KIT - Royal Tropical Institute
,
VU - Vrije Universiteit Amsterdam
Institute:
KIT - Royal Tropical Institute
Department:
Development Policy & Practice
Country:
Nigeria
Region:
West Africa
Training:
Master in International Health
Category:
research
Right:
@ 2015 Shobowale
Document type:
Thesis/dissertation
File:
hUAr6ly3VO_20171119153420843.pdf