Title:
First Line Non-Multidrug-Resistant Tuberculosis in India: A Neglected Problem
Authors:
Varghese, Bhanumati
Year:
2013
PAGE:
viii, 52
Language:
En
Subject:
Laboratory Quality Strengthening
Keywords:
First-Line Non-Mulitdrug Resistant Tuberculosis, TB, Treatment, Outcomes, India
Abstract:
Introduction: Tuberculosis that shows patterns of first-line drug resistance other than multidrug resistance occurs in large numbers in India. This problem receives relatively less attention compared to the more severe forms of drug-resistant tuberculosis. This thesis aims to explore the causation and consequences of this form of drug-resistant tuberculosis, and make recommendations to improve the management of these patients. Methods: The aims of the thesis are addressed by a literature review of the current magnitude of the problem, its current management, and the outcomes of this management for patients and society. Findings: First-line non-mutlidrug resistant tuberculosis is mainly created by irrational treatment regimens in the private sector. The enormous, unregulated private sector tuberculosis drug market also contributes to this. The treatment regimens for these patients in the national tuberculosis control program are not very effective as they are not tailored to the specific resistance patterns. The physical and socioeconomic consequences to individual patients can be severe. The public health consequences are also serious as drug resistant tuberculosis is propagated. Recommendations: Patients with first-line drug resistance other than multidrug resistance should be treated based on their DST patterns. The prescribing practices and sale of anti-tuberculosis drugs in the private sector must be strictly regulated.
Organization:
KIT - Royal Tropical Institute
,
VU - Vrije Universiteit Amsterdam
Institute:
KIT (Royal Tropical Institute)
Department:
Development, Policy and Practice
Country:
India
Region:
Southern Asia
Training:
Master in International Health (MIH)
Category:
Research
Right:
© 2013 Varghese
Document type:
Thesis/dissertation
File:
4QFFX3NnQr_20161103162032921.pdf