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In a recent
published study [1], 500 ADR reports were evaluated for causality using an
expert panel global introspection (GI) and 15 selected decisional
algorithms. The GI method was selected as the standard for comparisons in
the absence of a well established gold standard. Causality assessments
produced by both modalities were systematically compared and analysed. This
comparative analysis of decisional strategies under similar conditions aimed
the external validation of decisional algorithm's usefulness on causality
assessment of ADR. |