Title:
HIV Drug Resistance in Tanzania: A Literature Review of Socio-Cultural, Economic and Health Systems Determinants
Authors:
Msongole, Bernadeta Aggrey
Year:
2015
PAGE:
xi, 50
Language:
En
Subject:
Governance & HIV and AIDS
Keywords:
HIV Drug Resistance, HIVDR, Antiretroviral Therapy, ART, Determinants, Socio-Cultural, Health System
Abstract:
Background and Problem: Occurrence of HIV drug resistance (HIVDR) in Tanzania has been demonstrated in both antiretroviral therapy (ART) naive and patients on ART. Standardized ART regimens known to be effective at population level are used for treatment. HIVDR will reduce the effectiveness of ART therefore increasing HIV related morbidity and mortality. Objectives and Methodology: This study analysed socio-cultural, economic and health systems determinants of HIVDR, review interventions addressing HIVDR in SSA in order to make specific recommendations to minimize occurrence of HIVDR. Literature review was conducted and adapted framework from Roura was used to analyse the determining factors. Results: Presence of misinformation and false beliefs about HIV and ART and high indirect cost were identified as individual determinants for HIVDR. These were influenced by the existing traditional beliefs, some religious beliefs and practices and stigma. Health system weaknesses such as poor client retention mechanism, client overload at clinics, inadequate providers’ skills, shortage of health workers, poor access to services and frequent stock-out of antiretroviral drugs (ARVs) were also identified as determinants for occurrence of HIVDR. Conclusion and Recommendations: Occurrence of HIVDR in Tanzania is determined by factors occurring at community and health system level. Minimizing HIVDR needs interventions which focus on reducing healthcare worker workload through formulating policy on task shifting, reducing unnecessary clinic visits, ensuring continuous supply of ARVs, bringing services close to the community and analysing early warning indicators for HIVDR quarterly for prompt action.
Organization:
KIT - Royal Tropical Institute
,
VU - Vrije Universiteit Amsterdam
Institute:
KIT (Royal Tropical Institute)
Department:
Health Unit
Country:
Tanzania
Region:
Eastern Africa
Training:
Master of Public Health / International Course in Health Development (MPH/ICHD)
Category:
Research
Right:
© 2015 Msongole
Document type:
Thesis/dissertation
File:
DDRC6bI1jU_20161026131557255.pdf