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The cumulative
genotype-specific risks for the populations under investigation are
shown above. These risk
estimates are much easier to interpret clinically than relative
risks. For example, a Finnish
child with 2S haplotypes has a 7.1% chance of developing T1D through
age 35 years. If he/she had
1S haplotypes, their risk would be 2.3%.
So, even when individuals carry these susceptibility genes,
their actual likelihood of developing T1D is really quite low.
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