Key Point: Across the dose range, rosuvastatin and atorvastatin reduced TG to a similar extent.

Dose for dose, there were no significant differences in reductions in TG levels from baseline between rosuvastatin and atorvastatin (P<.002)

Rosuvastatin 10 mg decreased TG significantly more than pravastatin 10 mg to 20 mg (P<.002)

Rosuvastatin 20 mg decreased TG significantly more than simvastatin 40 mg, pravastatin 20 mg to 40 mg (P<.002)

Rosuvastatin 40 mg decreased TG significantly more than simvastatin 40 mg
and pravastatin 40 mg (P<.002)

Mean baseline TG: 172-187 mg/dL

Reference

Jones PH, Davidson MH, Stein EA, et al. Comparison of the efficacy and safety of rosuvastatin
versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR Trial). Am J Cardiol. 2003;93:152-160.