Key Point: Proteinuria appears to be a statin class effect. During controlled clinical

studies with rosuvastatin, proteinuria was observed with all statins and placebo.

The proteinuria that occurred with rosuvastatin was generally transient and
was not seen on follow-up visits1,2

The proteinuria was not associated with worsening renal function1,2

No renal monitoring required

No modification of rosuvastatin’s dosage is necessary when treating patients with
mild-to-moderate renal insufficiency (CLcr ³ 30 mL/min/1.73m2)

 

References

2.  Vidt DG, Cressman MD, Harris S, Pears JS, Hutchinson HG. Rosuvastatin-induced arrest in progression of renal disease. Cardiology. 2004;102:52-60.