 |
An important
clinical consideration is the generalizability of these data, particularly to women. In
the Women's Health Study, a prospective cohort of some 38,000 middle-aged, predominantly
postmenopausal American women who were free of cardiovascular disease at study entry, the
relative risk of future vascular events increased as the level of C-reactive protein went
from low-normal to high-normal. This was true for all vascular events as well as for the
specific combined endpoint of MI or stroke. Reference:
Ridker PM, Buring JE, Shih J, Matias M, Hennekens CH. Prospective study of C-reactive
protein and the risk of future cardiovascular events among apparently healthy women.
Circulation 1998;98:731-733.
WebsiteRidker PM et al. Circulation
1998;98:731-733. |
