If we now apply this simulation adjustment to our Jamaican population, we arrive at median survival figures of between 55 and 68 for women and between 49 and 57 for men. Median point values are now approximately 10 years higher than the US summaries (1).

Reference

(1) Platt OS, Brambilla DJ, Rosse WF, Milner PF, Castro O, Steinberg MH et al. Mortality in sickle cell disease. Life expectancy and risk factors for early death. N Engl J Med 1994; 330(23):1639-1644.