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Mean corpuscular volume: It depends on hemoglobin content in
the red blood cell, so in absence of other conditions a decrease in
hemoglobin is associated with a decrease in MCV. Ferritin: Even when ferritin is present within cells, a small amount circulates in plasma and permits estimation of total ferritin, been the earliest indicator of ID. As it has been mentioned before, Serum Ferritin expresses Iron Stores. During infancy Serum Ferritin concentration below 10 ng/ml are considered as the expression of depleted iron stores (Siimes et al, 1974; Thomas et al, 1977; Dallman et al, 1981). During infection or inflammation Serum Ferritin increases like other acute phase proteins, and then SF is not an accurate indicator in such situations. |