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If the study period is long enough to
observe the survival time of all subjects, as in some animal experiments, one may prefer
to use more common methods, such as the t-test and ordinary least square regression, to
analyse survival time as a continuous variable. However, in studies of human subjects
there often is censoring and the outcome cannot be analysed by the usual methods for
continuous data. Subjects
are often censored at different times, leading to unequal follow-up time. Analysis of the
probability of survival during the study period as a dichotomous variable (alive vs dead),
e.g. by a Chi-square test, would fail to account for this non-comparability between
subjects. |